Table 1.

Statistics for evaluating disease-related metabolite network

Disease name	Disease Ontology	Test node	Positive group	Version 2017	Version 2018
L-2-hydroxyglutaric aciduria	DOID:0050574	2	4	2	4
medium chain acyl-CoA dehydrogenase deficiency	DOID:0080153	1	16	15	16
short chain acyl-CoA dehydrogenase deficiency	DOID:0080154	1	4	3	4
Crohn’s colitis	DOID:0060192	5	8	3	16
cerebrotendinous xanthomatosis	DOID:4810	5	7	2	9
maple syrup urine disease	DOID:9269	6	23	17	24
abetalipoproteinemia	DOID:1386	3	4	1	4
celiac disease	DOID:10608	11	22	11	82
methylmalonic acidemia	DOID:14749	1	2	1	2
irritable bowel syndrome	DOID:9778	5	7	2	15
Fanconi syndrome	DOID:1062	1	2	1	5
citrullinemia	DOID:9273	6	8	2	8
inflammatory bowel disease 1	DOID:0110892	5	8	3	16
isovaleric acidemia	DOID:14753	2	11	9	12
type 2 diabetes mellitus	DOID:9352	1	27	27	27
aromatic L-amino acid decarboxylase deficiency	DOID:0090123	2	9	7	12
cholesterol ester storage disease	DOID:14502	1	2	1	2
congenital adrenal hyperplasia	DOID:0050811	15	18	3	28
Crohn’s disease	DOID:8778	5	8	3	16