Table 1.
MT-regulating genes differentially expressed in chemosensitive breast tumors
| Gene symbol | Gene name | Process |
| ASPM | Abnormal spindle microtubule assembly | MT minus-end binding, spindle organization |
| AURKB | Aurora kinase B | Ser/Thr protein kinase, spindle organization |
| GTSE1 | G2 and S phase-expressed 1 | MT plus-end binding, spindle organization, cell migration |
| KIF11 | Kinesin family member 11 | MT molecular motor, spindle organization |
| KIF14 | Kinesin family member 14 | MT molecular motor |
| KIF15 | Kinesin family member 15 | MT molecular motor |
| KIF18B | Kinesin family member 18B | MT depolymerizing, spindle organization |
| KIF20A | Kinesin family member 20A | MT molecular motor |
| KIF2C | Kinesin family member 2C | MT depolymerizing, spindle organization |
| KIF4A | Kinesin family member 4A | MT molecular motor, chromokinesin |
| KIFC1 | Kinesin family member C1 | MT molecular motor, spindle assembly |
| RACGAP1 | Rac GTPase-activating protein 1 | MT plus-end binding, spindle midzone assembly, cytokinesis |
| STMN1 | Stathmin 1 | MT-destabilizing, spindle organization |
| TPX2 | Targeting protein for Xklp2 | Aurora kinase A regulator, spindle organization |
| MAPT | Microtubule-associated protein tau | MT stabilizing, EB1 binding |
| MAST4 | Microtubule associated serine/threonine kinase family member 4 | Ser/Thr protein kinase |
| MTUS1 | Microtubule-associated tumor suppressor 1 | MT stabilizing, EB1 binding, tumor suppressor effects |
Properties of the 17 differentially regulated genes common to the 3 cohorts. Genes up-regulated in pCR tumors are in bold; those down-regulated are in italics.