Table 2.

Predictive factors of pCR in the R02 study

Variable	pCR (%)	Univariate analysis		Multivariate analysis
		OR (95% CI)	P value	OR (95% CI)	P value
Age
<50	8 (10.3)	0.44 (0.145–1.33)	0.147
>50	7 (20.6)
ER
Negative	10 (25)	4.46 (1.4–14.2)	0.011	4.66 (1.46–14.81)	0.0076
Positive	5 (6.9)
PR
Negative	13 (21.3)	6.5 (1.39–30.36)	0.017	1.88 (0.40–8.78)	0.281
Positive	2 (4)
HER2
Negative	9 (12.2)
Positive	6 (15.8)	1.35 (0.11–4.13)	0.597
Grade
III	10 (16.1)	2.01 (0.59–6.89)	0.262
I/II	4 (8.7)
Tumor stage
T2	10 (17.8)	2.21 (0.70–6.96)	0.172
T3–4	5 (8.9)
Nodal status
N0	8 (19.1)	2.05 (0.684–6.14)	0.199
N+	7 (10.3)
MTUS1 level
Low	8 (32)	5.37 (1.71–16.84)	0.0039	12.16 (3.88–38.07)	<0.0001
Medium/high (n = 7)	7 (8.1)
Continuous*		1.78 (1.19–2.76)	0.005

^*Entered as continuous variable (probe set 212096_s_at values). Significant P values are indicated in bold.