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The potential direct target genes of MRTFB include 2 known tumor suppressors. (A) Venn diagram of comparison of significantly down-regulated genes among MRTFB siRNA samples. (B) Two known tumor suppressors were among the 8 common down-regulated genes that are potentially direct targets of MRTFB transcriptional activity. (C) PCR results validated the significant expression level changes of the 8 common down-regulated target genes of MRTFB’s identified by RNA-seq.
