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. 2019 Nov 4;116(47):23527–23533. doi: 10.1073/pnas.1905381116

Fig. 1.

Fig. 1.

HRF identifies POT1-N and POT1-TPP1 residues undergoing environmental changes upon binding of differing telomere ssDNA substrates. (A) Normalized modification ratio of POT1-N-hT12/POT1-N-hT72 versus normalized modification ratio of POT1-N/POT1-N-hT12 for all detectable POT1-N residues. Gray squares indicate boundaries of mean ± 3 SD (solid) and mean ± 2 SD (dashed). (B) POT1 and (C) TPP1 residue modification ratios of PT-hT12/PT-hT72 versus normalized modification ratio of PT/PT-hT12 in the context of POT1-TPP1 binding to ssDNA substrates. Data are plotted as described in A.