Table 2.

PFAS Tested for Selective DA Neurotoxicity

PFAS	Exposure Level Range Tested for Neurodegeneration (ppm)	Threshold for DA Neurodegeneration	Threshold for Non-DA Neurodegeneration	Selective Neurodegeneration (Yes/No)
PFOA	25–200	Not found	Not tested	Not detected at tested exposure levels
PFOS	25–200	25	100	Yes
GenX	25–200	200	Not tested	Yes

Numerous PFAS were evaluated for evidence of neurodegeneration. Selective DA neurodegeneration was identified where the threshold (lowest does) to induce statistically significant DA neurodegeneration was lower than that to induce non-DA neurodegeneration (significant effects on GABA, 5-HT, or ACh neurons)—lowest exposure level to affect one of these populations is reported. ND = not detectable.