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. 2019 Aug 29;172(2):252–264. doi: 10.1093/toxsci/kfz196

Figure 3.

Figure 3.

Stably overexpressing c-Myc alone in parental BEAS-2B cells induces CSC-like property and cell transformation. A, Western blot analysis of c-Myc expression level in parental BEAS-2B cells and parental BEAS-2B vector control or c-Myc stable overexpression (BEAS-2B-c-Myc OE) cells. B, MTT analysis of the growth curve of parental BEAS-2B cells and parental BEAS-2B vector control or c-Myc stable overexpression (BEAS-2B-c-Myc OE) cells. The results are presented as means ± standard deviations (n = 6). Quantitation of suspension culture sphere formation (C) and soft agar colony formation (D) by parental BEAS-2B vector control and c-Myc stable overexpression (BEAS-2B-c-Myc OE) cells. The results are presented as means ± standard deviations (n = 3). *p < .05, compared with BEAS-2B-Vector Control cells.