Table 1.
Bone marrow MN data after acute (2 days) acetamide exposure in mice.
| Dose (mg/kg/day) | Animals Tested | MN-PCE counts | % MN-PCE (s.d.) | P/E Ratio (s.d.) | Total PCE Counted | |
|---|---|---|---|---|---|---|
| Male | Distilled water | 6 | 2,0,1,1,0,1 | 0.017 (0.015) | 0.491 (0.024) | 27063 |
| 250 | 6 | 1,2,1,0,0,1 | 0.017 (0.015) | 0.496 (0.025) | 27060 | |
| 1000 | 6 | 0,1,0,0,1,2 | 0.013 (0.016) | 0.498 (0.018) | 27043 | |
| 2000 | 6 | 2,1,1,0,1,0 | 0.017 (0.015) | 0.493 (0.024) | 27086 | |
| 1 (Mitomycin-C) |
6 |
47,40,49,82,65,72 |
1.3081 (0.363) |
0.511 (0.039) |
27127 |
|
| Female | Distilled water | 6 | 1,1,1,0,0,1 | 0.013 (0.010) | 0.521 (0.025) | 27077 |
| 250 | 6 | 1,0,1,2,0,3 | 0.025 (0.027) | 0.515 (0.022) | 27041 | |
| 1000 | 6 | 0,2,1,0,2,1 | 0.020 (0.018) | 0.522 (0.031) | 27095 | |
| 2000 | 6 | 0,1,2,1,0,1 | 0.017 (0.015) | 0.510 (0.025) | 27054 | |
| 1 (Mitomycin-C) | 6 | 65,43,57,54,48,96 | 1.3401 (0.422) | 0.499 (0.018) | 27066 |
1Denotes significant difference (p < 0.01) compared to species and sex matched negative control.