Table 2.
Bone marrow MN data after acute (2 days) acetamide exposure in rats.
| Dose (mg/kg/day) | Animals Tested | MN-PCE counts | % MN-PCE (s.d.) | P/E Ratio (s.d.) | Total PCE Counted | |
|---|---|---|---|---|---|---|
| Male | Distilled water | 6 | 0,0,2,0,1,1 | 0.013 (0.016) | 0.494 (0.031) | 27072 |
| 250 | 6 | 1,1,1,1,0,0 | 0.013 (0.010) | 0.477 (0.018) | 27060 | |
| 1000 | 6 | 2,1,1,2,0,0 | 0.020 (0.018) | 0.498 (0.016) | 27100 | |
| 2000 | 6 | 1,1,0,1,2,0 | 0.017 (0.015) | 0.497 (0.027) | 27097 | |
| 1 (Mitomycin-C) |
6 |
43,51,46,39,35,38 |
0.92711 (0.129) |
0.514 (0.026) |
27157 |
|
| Female | Distilled water | 6 | 1,2,0,1,1,0 | 0.017 (0.015) | 0.495 (0.009) | 27223 |
| 250 | 6 | 1,2,1,2,0,0 | 0.020 (0.018) | 0.497 (0.028) | 27079 | |
| 1000 | 6 | 2,0,1,2,1,0 | 0.020 (0.018) | 0.491 (0.020) | 27055 | |
| 2000 | 6 | 0,1,1,1,0,1 | 0.013 (0.010) | 0.508 (0.025) | 27115 | |
| 1 (Mitomycin-C) | 6 | 37,59,60,35,34,34 | 0.95711 (0.283) | 0.502 (0.028) | 27054 |
1Denotes significant difference (p < 0.01) compared to species and sex matched negative control.