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Effects of Tan IIA on EGF- and TGF-β1-induced migration and invasion of HepG2 cells. The migration and invasion of HepG2 cells that were untreated or treated with (A) 20 ng/ml EGF, (B) 10 ng/ml TGF-β1 and Tan IIA (0.5, 1 and 2 µM) were analyzed by wound healing and Transwell assays, respectively. Scale bars, 100 µm. **P<0.01 vs. the control group; #P<0.05, ##P<0.01 vs. the EGF or TGF-β1 group. EGF, epidermal growth factor; Tan IIA, tanshinone IIA; TGF, transforming growth factor.
