Table I.
Characteristic of the selected variables.
| MAC | NMAC | ||
|---|---|---|---|
| Characteristics | Patients, n (%) | Patients, n (%) | P-value |
| Age (years) | <0.001 | ||
| <50 | 1,744 (13.38) | 6,864 (11.08) | |
| 50–59 | 2,359 (18.10) | 12,719 (20.53) | |
| 60–69 | 2,984 (22.89) | 15,221 (24.57) | |
| 70–79 | 3,293 (25.26) | 15,874 (25.62) | |
| ≥80 | 2,655 (20.37) | 11,280 (18.21) | |
| Sex | <0.001 | ||
| Female | 6,738 (51.69) | 30,108 (48.59) | |
| Male | 6,297 (48.31) | 31,850 (51.41) | |
| Race | <0.001 | ||
| Caucasian | 10,705 (82.13) | 49,913 (80.56) | |
| African American | 1,473 (11.30) | 6,623 (10.69) | |
| Others or unknown | 857 (6.57) | 5,422 (8.75) | |
| Location | <0.001 | ||
| Cecum | 3,045 (23.36) | 9,740 (15.72) | |
| Appendix | 824 (6.32) | 241 (0.39) | |
| Ascending colon | 2,544 (19.52) | 8,018 (12.94) | |
| Hepatic flexure | 707 (5.42) | 2,191 (3.54) | |
| Transverse colon | 1,018 (7.81) | 3,882 (6.27) | |
| Splenic flexure | 377 (2.89) | 1,654 (2.67) | |
| Descending colon | 503 (3.86) | 2,835 (4.58) | |
| Sigmoid colon | 1,695 (13.00) | 15,104 (24.38) | |
| Rectosigmoid | 645 (4.95) | 5,716 (9.23) | |
| Junction | |||
| Rectum | 1,464 (11.23) | 11,738 (18.95) | |
| Unknown | 213 (1.63) | 839 (1.35) | |
| Tumor size (cm) | <0.001 | ||
| ≤2 | 1,817 (13.94) | 9,167 (14.80) | |
| >6 | 3,036 (23.29) | 7,393 (11.93) | |
| 2–4 | 3,105 (23.82) | 19,393 (31.30) | |
| 4–6 | 3,756 (28.81) | 14,707 (23.74) | |
| Unknown | 1,321 (10.13) | 11,298 (18.23) | |
| AJCC 6th stage (19) | <0.001 | ||
| 0/(Tis) | 51 (0.39) | 2,823 (4.56) | |
| I | 1,677 (12.87) | 16,873 (27.23) | |
| IIA | 3,792 (29.09) | 14,999 (24.21) | |
| IIB | 862 (6.61) | 1,960 (3.16) | |
| IIIA | 318 (2.44) | 2,177 (3.51) | |
| IIIB | 2,315 (17.76) | 9,378 (15.14) | |
| IIIC | 1,629 (12.50) | 5,326 (8.60) | |
| IV | 2,148 (16.48) | 7,141 (11.53) | |
| Unknown | 243 (1.86) | 1,281 (2.07) | |
| Grade | <0.001 | ||
| Low grade (I and II) | 9,283 (71.22) | 47,290 (76.33) | |
| High grade | 2,612 (20.04) | 10,176 (16.42) | |
| (III and IV) | |||
| Unknown | 1,140 (8.75) | 4,492 (7.25) | |
| Regional nodes positive | <0.001 | ||
| ≥10 | 6600 (50.63) | 33151 (53.51) | |
| 0 | 3015 (23.13) | 12971 (20.94) | |
| 1–3 | 1824 (13.99) | 6545 (10.56) | |
| 4–9 | 1596 (12.24) | 9291 (15.00) | |
| Chemotherapy | <0.001 | ||
| No | 7,352 (56.40) | 39,410 (63.61) | |
| Yes | 5,683 (43.60) | 22,548 (36.39) | |
| Radiotherapy | <0.001 | ||
| No | 11,474 (88.02) | 53,499 (86.35) | |
| Yes | 1,520 (11.66) | 8,241 (13.30) | |
| Unknown | 41 (0.31) | 218 (0.35) | |
| Marital status | <0.001 | ||
| Married | 7,242 (55.56) | 35,752 (57.70) | |
| Unmarried | 5,413 (41.53) | 23,799 (38.41) | |
| Unknown | 380 (2.92) | 2,407 (3.88) | |
| CEA status | <0.001 | ||
| Negative/normal | 3,776 (28.97) | 18,665 (30.13) | |
| Positive/elevated | 3,619 (27.76) | 12,903 (20.83) | |
| Unknown/borderline | 5,640 (43.27) | 30,390 (49.05) | |
MAC, mucinous adenocarcinoma; NMAC, non-mucinous adenocarcinoma; CEA, carcinoembryonic antigen. Significant results are in bold.