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. Author manuscript; available in PMC: 2019 Nov 25.
Published in final edited form as: J Pediatr Hematol Oncol. 2018 Apr;40(3):208–215. doi: 10.1097/MPH.0000000000001112

Figure 4. Doxorubicin in cardiac tissue is reduced by exercise independent of a decrease in microvessel density.

Figure 4

A) Doxorubicin concentration in cardiac tissue was measured by spectrophotometry. Graphs show the mean +/− standard deviation for hearts from non-exercised vs. exercised tumor-bearing mice. B) Representative CD31 (red, endothelial cells) staining of heart sections from each treatment group of nude, tumor-bearing mice. Graphs show the mean +/− standard deviation of CD31:DAPI (endothelial cell: total nuclei) ratio for 5 sections per animal.