Table 1.
Participant characteristics split out by assessment centre, and for the full sample.
| Manchester |
Reading |
Newcastle |
Full Sample |
|||||
|---|---|---|---|---|---|---|---|---|
| M(SD)a | N | M(SD) | N | M(SD) | N | M(SD) | N | |
| Age (years) | 62.818 (7.484) | 22,037 | 65.202 (7.299) | 866 | 63.962 (7.379) | 6101 | 63.130 (7.480) | 29,004 |
| Sex (F:M) | 11,315: 10,722 | 22,037 | 453: 413 | 866 | 3256: 2845 | 6101 | 15,024: 13,980 | 29,004 |
| Matrix Reasoning | 8.047 (2.113) | 8994 | 8.277 (2.045) | 850 | 7.904 (2.124) | 5671 | 8.007 (2.115) | 15,515 |
| Symbol-Digit | 19.212 (5.255) | 9019 | 18.753 (5.152) | 858 | 18.714 (5.235) | 5681 | 19.005 (5.247) | 15,558 |
| VNR | 6.778 (2.070) | 20,455 | 6.800 (2.058) | 860 | 6.466 (2.001) | 5668 | 6.713 (2.061) | 26,983 |
| TMTba | 496 (236) | 9103 | 512 (230) | 866 | 503(236) | 5710 | 499 (235) | 15,679 |
| TBV | 1,170,062 (110900) | 17,223 | – | 0 | 1,154,425 (110376) | 3104 | 1,167,674 (110960) | 20,327 |
| GM | 618,392 (55474) | 17,226 | – | 0 | 611,240 (54923) | 3104 | 617,300 (55448) | 20,330 |
| NAWM | 547,110 (61736) | 16,146 | – | 0 | 537,269 (61090) | 3062 | 545,541 (61737) | 19,208 |
| WMH a | 2500 (3641) | 16,146 | – | 0 | 3290(4506) | 3062 | 2622 (3816) | 19,208 |
| gFA | 0.025 (0.824) | 15,448 | – | 0 | −0.131 (0.834) | 2989 | 0.00 (0.827) | 18,437 |
| gMD | 0.022 (0.918) | 15,448 | – | 0 | −0.113 (0.907) | 2989 | 0.00 (0.918) | 18,437 |
Note. Means and standard deviations (SD) reported, except for amedian and interquartile ranges are given. VNR: verbal numerical reasoning, TMTb: Trail Making Test Part b, TBV: total brain volume, GM: grey matter volume, NAWM: normal-appearing white matter volume, WMH: white matter hyperintensity volume, gFA: general factor of white matter fractional anisotropy, gMD: general factor of white matter mean diffusivity.