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. 2019 Nov 18;9:1267. doi: 10.3389/fonc.2019.01267

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Copyright © 2019 Kersy, Loewenstein, Lubezky, Sher, Simon, Klausner and Lahat.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Omental tissue promotes tumor growth in vivo. (A) Growth and weight of AGS tumors was facilitated in mice after incubation with omental tissue CM (n = 15). Graphs represent the average of three repeated experiments ± SD (P < 0.005); (B) Images of representative tumor and mice; (C) Human omental tissue CM increase the proliferation (Ki-67) and microvessel density (CD31) of mice xenografts. Representative images are shown on the left (H&E, ×200; Ki-67, ×200; CD31, ×200). Immunohistochemistry (IHC) quantification is shown on the right. n = 10 in tissues of each site. *P < 0.05; **P < 0.01; ***P < 0.001.