Table 2.
Placental histology and cause of death in late second trimester miscarriages (demise before 22 weeks’ gestation).
| Placental Histology | Autopsy | Maternal age | Gravidy | Parity | GA at delivery | GA according to FL | Birth weight (g) | Placental weight (g) | Histological Findings |
|---|---|---|---|---|---|---|---|---|---|
| Yes | Yes | 17 | 1 | 0 | 21w2d | 21w6d | 408 | 154 | Acute chorioamnionitis, abruption |
| Yes | Yes | 26 | 2 | 1 | 22w0d | 16w3d | 60 | 42 | Maternal vascular malperfusion |
| Yes | Yes | 17 | 1 | 0 | 22w6d | 16w6d | 160 | 140 | Chronic villitis with OFV, CMV |
| Yes | Yes | 20 | 2 | 1 | 24w4d | 17w5d | 148 | 70 | Early amnion rupture with anhydramnios, cord obstruction |
| Yes | Yes | 25 | 2 | 1 | 21w3d | 14w3d | 50 | 41 | Maternal vascular malperfusion |
| No | Yes | 36 | 1 | 0 | 21w1d | 23w1d | 450 | N/A | N/A |
| Yes | Yes | 32 | 2 | 1 | 21w6d | 22w6d | 410 | 104 | Acute chorioamnionitis, abruption |
| Yes | Yes | 17 | 1 | 0 | 20w6d | 20w2d | 331* | 82 | Acute chorioamnionitis |
| Yes | Yes | 23 | 2 | 0 | 20w6d | 14w4d | 103* | 49 | Termination of pregnancy for Turner syndrome |
| Yes | No | 32 | 2 | 3 | 19w3d | N/A | N/A | 282 | Acute chorioamnionitis, abruption, maternal vascular malperfusion |
| Yes | Yes | 31 | 4 | 3 | 21w2d | 22w1d | 336* | 132 | Abruption |
| Yes | Yes | 29 | 2 | 1 | 22w3d | 15w2d | 62* | 31 | Maternal vascular malperfusion, abruption |
| No | Yes | 22 | 2 | 1 | 21w1d | 16w3d | 71* | N/A | N/A |
| Yes | Yes | 23 | 3 | 0 | 21w4d | 22w4d | 400 | 131 | Maternal vascular malperfusion, abruption |
OFV = Obliterative fetal vasculopathy.
*
No birth weight available, only autopsy weight; CMV = cytomegalo virus; GA = gestational age; FL = foot length; N/A = not available.