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. 2019 Nov 25;14(11):e0225425. doi: 10.1371/journal.pone.0225425

Fig 5. Micrographs showing alterations on the ultrastructure of the anterior region of Schistosoma mansoni adult male worms exposed to NJ05 or NJ07.

Fig 5

Scanning electron microscopy of worms exposed for 2 days to 25 μM NJ05 (panels 5–8), 25 μM NJ07 (panels 9–12) or vehicle (0.1% DMSO) (panels 1–4). Note that the size scale bar is shown within the black thin line below each image; panels 1 and 2: Control worms (Bar = 500 μm; 100 μm) presented the fully paired couple; panels 3 and 4: Anterior region of control male presented normal oral and ventral suckers tegument (Bar = 50 μm; 30 μm); panels 5 and 6: Anterior region of adult male worm treated with 25 μM NJ05 (Bar = 500 μm; 100 μm); panels 7 and 8: Male oral and ventral suckers presented tegument peeling (Bar = 50 μm); panels 9 and 10: Anterior region of male adult worm treated with 25 μM NJ07 (Bar = 500 μm; 100 μm); panels 11 and 12: Male oral and ventral suckers presented tegument without structural alterations (Bar = 50 μm). f: female; os: oral sucker; vs: ventral sucker; gc: gynecophoral canal; la: lesion area; cp: ciliated papillae.