Appendix 1—table 1. Effectiveness of the viral challenge in asthmatic and healthy participants, respectively.
A participant is considered to have a successful viral inoculation if any one of the three tests is positive. one indicates positive response and 0 indicates a failed response in the corresponding tests indicated in columns.
| Study volunteers | Responders by seroconversion | Responders by RVPCR | Description of symptoms |
|---|---|---|---|
| 01A | 1 | 1 | Running nose, blocked nose and cough |
| 02A | 0 | 1 | Sore throat, blocked nose, full head, coughing and sneezing. |
| 04A | 1 | 0 | Slight symptoms of cold, very mild |
| 05A | 0 | 1 | No clear symptoms |
| 06A | 1 | 1 | Symptoms of cold |
| 07A | 1 | 1 | Minor sore throat, dripping nose, shortness of breath. |
| 08A | 1 | 0 | Sore throat, Probably very mild effect, no other symptoms |
| 09A | 0 | 1 | Running nose, head ache, fever |
| 10A | 1 | 1 | Very mild symptoms |
| 11A | 1 | 1 | Very mild symptoms |
| 12A | 0 | 1 | Cough, blocked nose |
| 13A | 0 | 1 | No clear symptoms |
| 01H | 0 | 1 | Sore throat |
| 03H | 0 | 1 | Sore throat and blocked nose |
| 05H | 1 | 1 | Cough, blocked nose and headache |
| 06H | 0 | 1 | No clear symptoms observed |
| 07H | 1 | 0 | Sneezing, itchy eyes and a little bit of a cough |
| 08H | 1 | 1 | Little bit sore throat |
| 09H | 1 | 1 | Sore throat and little cough |
| 11H | 0 | 0 | Blocked nose and sputum |
| 12H | 1 | 1 | Running nose and sneeze |
| 13H | 1 | 1 | No clear symptoms |
| 14H | 0 | 1 | Cough and blocked nose |
| 15H | 1 | 0 | No clear symptoms |