Table 5.

Associations of 12‐month LCA classes and underlying 12‐month DSM‐IV disorders with role impairment outcomes (n = 14,348)[Link]

	Home		Work		Relationship		Social
	OR	95% CI	OR	95% CI	OR	95% CI	OR	95% CI
I. Any role impairment
A. Classes
C1	2.2*	[1.0, 4.6]	7.1*	[3.9, 12.9]	3.2*	[1.6, 6.5]	7.8*	[3.8, 19.1]
C2	1.3	[0.9, 1.8]	3.9*	[3.0, 5.1]	2.4*	[1.8, 3.3]	3.5*	[2.6, 5.5]
C3	2.5*	[2.0, 3.0]	5.2*	[4.4, 6.2]	4.8*	[4.0, 5.7]	5.9*	[5.1, 7.7]
C4	1.4*	[1.2, 1.7]	2.2*	[1.9, 2.6]	2.1*	[1.9, 2.4]	2.4*	[2.1, 3.1]
C5	1.6*	[1.5, 1.9]	2.2*	[2.0, 2.4]	2.2*	[2.0, 2.4]	2.3*	[2.2, 2.6]
F 5	29.3*		90.5*		88.9*		90.8*
B. Internalizing disorders
Major depressive episode	1.7*	[1.5, 2.0]	1.6*	[1.3, 1.8]	2.0*	[1.7, 2.3]	2.0*	[1.6, 2.3]
Bipolar spectrum disorder	1.9*	[1.3, 2.7]			1.6*	[1.1, 2.3]
Generalized anxiety disorder
Panic disorder	1.8*	[1.3, 2.4]	2.3*	[1.6, 3.3]	1.9*	[1.4, 2.7]	2.3*	[1.5, 3.6]
C. Externalizing disorders
Alcohol use disorder	1.4*	[1.1, 1.7]					0.8*	[0.6, 0.9]
ADHD	1.8*	[1.5, 2.1]	1.5*	[1.2, 1.8]	1.5*	[1.2, 1.7]	1.2	[1.0, 1.5]
Drug use disorder	2.1*	[1.5, 3.1]			1.6*	[1.1, 2.2]	1.6*	[1.1, 2.3]
Fv [Link]	12.0*		17.2*		15.6*		17.9*
II. Severe role impairment
A. Classes
C1	4.7*	[2.5, 8.9]	5.1*	[3.3, 7.9]	10.0*	[6.7, 14.8]	7.1*	[4.5, 11.2]
C2	2.2*	[1.4, 3.6]	2.7*	[1.9, 3.8]	5.2*	[3.9, 7.0]	3.4*	[2.4, 4.7]
C3	3.5*	[2.4, 5.2]	4.0*	[3.1, 5.2]	6.4*	[5.0, 8.2]	6.4*	[4.9, 8.3]
C4	2.1*	[1.4, 3.1]	1.8*	[1.4, 2.3]	2.8*	[2.2, 3.6]	2.6*	[2.0, 3.4]
C5	2.0*	[1.4, 2.8]	1.4*	[1.1, 1.8]	1.8*	[1.4, 2.3]	2.2*	[1.7, 2.8]
F 5	9.6*		23.2*		54.6*		40.8*
B. Internalizing disorders
Major depressive episode	1.7*	[1.4, 2.2]	2.2*	[1.9, 2.7]	2.0*	[1.7, 2.3]	2.2*	[1.9, 2.6]
Bipolar spectrum disorder
Generalized anxiety disorder
Panic disorder	1.6*	[1.2, 2.2]	1.7*	[1.3, 2.2]			1.3*	[1.0, 1.7]
C. Externalizing disorders
Alcohol use disorder
ADHD	1.8*	[1.4, 2.4]	1.8*	[1.5, 2.1]			1.3*	[1.1, 1.5]
Drug use disorder	1.7*	[1.1, 2.6]
Fv [Link]	10.2*		37.0*		65.8*		28.9*

Based on forward stepwise regression models that included all five latent class analysis (LCA) classes C1–C5 in addition to all individual disorders that stepped in at the.05 level of significance using MI‐adjusted two‐sided tests.

bv: the number of mental disorders assessed in Parts II and III of the table.

^* Significant at the.05 level, two‐sided MI‐corrected test.