Comparison 6. QUIPS ROB domain ratings (work participation outcome (closest to 12 months); dichotomous measure of expectations (adjusted)).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 'Participation' domain	12		Odds Ratio (Random, 95% CI)	Subtotals only
1.1 Studies with low ROB	6		Odds Ratio (Random, 95% CI)	2.76 [1.48, 5.17]
1.2 Studies with moderate/high ROB	6		Odds Ratio (Random, 95% CI)	2.16 [1.41, 3.31]
2 'Attrition' domain	12		Odds Ratio (Random, 95% CI)	Subtotals only
2.1 Studies with low ROB	10		Odds Ratio (Random, 95% CI)	2.72 [2.05, 3.60]
2.2 Studies with moderate/high ROB	2		Odds Ratio (Random, 95% CI)	1.04 [1.02, 1.06]
3 'Prognostic factor' domain	12		Odds Ratio (Random, 95% CI)	Subtotals only
3.1 Studies with low ROB	0		Odds Ratio (Random, 95% CI)	0.0 [0.0, 0.0]
3.2 Studies with moderate/high ROB	12		Odds Ratio (Random, 95% CI)	2.43 [1.64, 3.62]
4 'Outcome' domain	12		Odds Ratio (Random, 95% CI)	Subtotals only
4.1 Studies with low ROB	10		Odds Ratio (Random, 95% CI)	2.41 [1.76, 3.29]
4.2 Studies with moderate/high ROB	2		Odds Ratio (Random, 95% CI)	2.31 [0.82, 6.51]
5 'Confounding' domain	12		Odds Ratio (Random, 95% CI)	Subtotals only
5.1 Studies with low ROB	8		Odds Ratio (Random, 95% CI)	2.03 [1.34, 3.07]
5.2 Studies with moderate/high ROB	4		Odds Ratio (Random, 95% CI)	3.10 [2.36, 4.07]
6 'Analysis and Reporting' domain	12		Odds Ratio (Random, 95% CI)	Subtotals only
6.1 Studies with low ROB	9		Odds Ratio (Random, 95% CI)	2.26 [1.46, 3.50]
6.2 Studies with moderate/high ROB	3		Odds Ratio (Random, 95% CI)	3.03 [1.91, 4.78]