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. 2019 Nov 11;129(12):5474–5488. doi: 10.1172/JCI121208

Figure 4. HFD induces elevated systemic immune activation and inflammation in SIV-infected NHPs.

Figure 4

Frequencies of CD38 and HLA-DR coexpressing CD8+ T cells (A), CRP levels (B) and RANTES levels (C) to baseline levels in AGMs, as well as in PTMs (D–F), are compared at key time points of SIV infection within HFD group with Friedman test corrected for multiple comparisons, and between HFD and control groups with the Kruskal-Wallis test. Data are presented as individual values with medians. Sample size (n) and P values are presented on graphs. Ac, acute infection; BL, baseline (preinfection pre-HFD); Chr, chronic infection; Fat, preinfection post-HFD; Nx, necropsy.