Skip to main content
. 2019 Nov 11;129(12):5474–5488. doi: 10.1172/JCI121208

Figure 8. HFD-induced liver steatosis and fibrosis in SIV-infected NHPs.

Figure 8

Representative images of HFD-induced liver steatosis in AGMs and PTMs (A). Representative images of liver stained with Masson trichrome showing collagen (blue) collected before infection, at 9 days after infection, and at necropsy from control and HFD-receiving PTMs (B). Original magnifications: ×200. Quantification of the percent area of collagen is shown in the right panel. Fold increase of hyaluronic acid levels vs baseline levels in AGMs (C) and in PTMs (D) are compared at key time points of SIV infection within HFD group with Friedman test corrected for multiple comparisons and between HFD and control groups with Kruskal-Wallis test. Data are presented as individual values with medians. Sample size (n) and P values are presented on graphs. Ac, acute infection; BL, baseline (preinfection pre-HFD); Chr, chronic infection; Fat, preinfection post-HFD; Nx, necropsy.