Table 1.
Clinical characteristics of 10 cases (including the present case) of concurrent anti-GBM nephritis and IgA nephropathy in the literature
| Characteristic | Percent |
|---|---|
| Male:Female ratio | 4:6 (1:1.5) |
| Age, mean (range, yr) | 43 (27–60) |
| History of upper respiratory tract infection | 20 |
| History of hematuria or proteinuria | 40 |
| Symptoms or signs | |
| Hemoptysis or abnormal chest findings | 0 |
| Oliguria | 10 |
| Nephrotic syndrome | 20 |
| Laboratory findings | |
| Proteinuria, mean (g/day) | 2.6 |
| Hematuria | 100 |
| Creatinine, mean (mg/dL) | 5.0 |
| Anti-GBM antibody titer, mean (EU/mL) | 180 |
| Percentage of crescents, mean | 59 |
| Treatment | |
| Intravenous methyl-PD + Oral-PD | 100 |
| Cyclophosphamide | 60 |
| Mycophenolate mofetil | 20 |
| Methotrexate | 10 |
| Plasmapheresis | 30 |
| Prognosis | |
| Improved | 60 |
| Not improved | 40 |
| Expired (due to gastrointestinal bleeding) | 10 |
| Dialysis | |
| Independent | 60 |
| Dependent | 30 |
GBM, glomerular basement membrane; PD, prednisolone.