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. 2019 Nov 25;9:17445. doi: 10.1038/s41598-019-53822-x

Figure 3.

Figure 3

Micro-CT based evaluation of bone parameters in the scan group using different VOIS: total VOI (TOT) - defect and adjacent bone fragments (top), defect VOI (DC + DP) – defect center and periphery (bottom). (a,d) Bone formation rate (solid) and bone resorption rate (dashed line) in the femur defect (TV) given in percent per day. (b,e) Bone volume (BV) normalized to TV (DC + FC for TOT and DC for DC + DP). (c,f) Degree of bone mineralization given as ratio of bone volume with a density ≥645 mg HA/cm3 to the total osseous volume in the defect (threshold ≥395 mg HA/cm3). n = 10; * indicates p < 0.05 between consecutive weeks determined by Friedman test with Dunn correction for multiple comparisons (a–e)/ repeated measurements ANOVA with Bonferroni correction (f).