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Muscle protein hypercatabolism is counteracted by ZA administration in C-treated mice. mRNA expression for the ubiquitin ligases Atrogin-1 and MuRF-1 in the quadriceps muscle of mice treated with cisplatin and/or ZA (n = 4–5). Data are shown as means ± SEM. Significance of the differences: *p < 0.05, **p < 0.01 vs. V; $p < 0.05, $$p < 0.01 vs. C; &&p < 0.01 vs. ZA.
