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Cisplatin causes severe loss of bone mass. 3D rendering of microCT-based analysis of trabecular bone in femurs from mice receiving V (n = 4) or C (n = 7) (A). Assessment of trabecular bone volume (BV/TV; expressed as %), trabecular number (Tb.N; expressed as 1/μm), trabecular thickness (Tb.Th; expressed as μm) and trabecular separation (Tb.Sp; expressed as μm) in femoral bones (B). Data are reported as means ± SEM. Significance of the differences: ***p < 0.001 vs. V.
