Table 2.
Diagnostic performance of axillary US and standard breast MRI for differentiation between pN1 and pN2–3.
| US (n = 49) | MRI reader 1 (n = 49) | p-valuea US vs MRI1 | MRI reader 2 (n = 49) | p-valueb US vs MRI2 | |
|---|---|---|---|---|---|
| Sensitivity |
97.0% (32/33) [84.2–99.9] |
84.8% (28/33) [68.1–94.9] |
0.10 |
84.8% (28/33) [68.1–94.9] |
0.10 |
| Specificity |
12.5% (2/16) [1.6–38.3] |
43.8% (7/16) [19.8–70.1] |
0.03 |
50.0% (8/16) [24.7–75.3] |
0.01 |
| PPV |
69.6% (32/46) [54.2–82.3] |
75.7% (28/37) [58.8–88.2] |
0.13 |
77.8% (28/36) [60.8–89.9] |
0.06 |
| NPV |
66.7% (2/3) [9.4–99.2] |
58.3% (7/12) [27.7–84.8] |
0.77 |
61.5% (8/13) [31.6–86.1] |
0.85 |
| Accuracy |
69.4% (34/49) [54.6–81.7] |
71.4% (35/49) [56.7–83.4] |
0.99 |
73.5% (36/49) [58.9–85.1] |
0.77 |
Abbreviations: US, ultrasound; PPV, positive predictive value; NPV, negative predictive value; MRI1, MRI reader 1; MRI2, MRI reader 2.
aMcNemar and generalised score test for comparison of diagnostic performance parameters between US and breast MRI of reader 1.
bMcNemar and generalised score test for comparison of diagnostic performance parameters between US and breast MRI of reader 2.
Data in parenthesis are absolute numbers. Data in brackets are 95% confidence intervals.