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. 2019 Nov 25;9(12):94. doi: 10.1038/s41408-019-0254-0

Fig. 4. Pertinent subgroup analyses.

Fig. 4

a Kaplan–Meier curves are shown for patients as stratified by their cytogenetics (high risk, “Hi,” defined as t(4;14), t(14;16) and/or del(17p) or standard risk, “Std”) and presence or absence of +1q. HR for Hi/+1q vs Std/+1q = 3.34 (1.83-6.08); Hi/+1q vs Hi = 3.97 (1.14-13.81); Std/+1q vs Std = 1.39 (0.86-2.24). b Kaplan–Meier curves for patients stratified by copy number of chromosome 1q by FISH. HR for 3 vs 2 copies = 1.47 (0.88-2.45); 4 vs 2 copies = 2.45 (1.38-4.35); 4 vs 3 copies = 1.67 (0.89-3.12). c PFS of standard risk patients stratified by 1q copy number. HR for 2 vs 4 copies = 0.44 (0.23-0.84); 3 vs 4 copies = 0.34 (0.15-0.76); 2 vs 3 copies = 1.28 (0.66-2.46). d PFS of high-risk patients stratified by 1q copy number. HR for 2 vs 4 copies = 0.31 (0.07-1.32), 3 vs 4 copies = 2.06 (0.67-6.29); 2 vs 3 copies = 0.15 (0.04-0.61).