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. 2019 Nov 25;10:5346. doi: 10.1038/s41467-019-13064-x

Fig. 3.

Fig. 3

Structure of triplex and the functional significance of Tri1 N-anchor. a Distribution of triplexes Ta, Tb, Tc, Td, and Te among three types of hexons (C, E, and P) and a penton. b Enlarged view of a triplex Td with three adjacent hexon MCP subunits labeled (C1, E5, and P4). MCP subunits have been faded. c Further enhanced structure of triplex Td, rotated 90 degrees clockwise on the x axis from b. d Model of Tri1 with labeled domains. e Top and bottom views of b, showing that triplex Td is anchored to the capsid floor by the “V”-shaped Tri1 N-anchor (in pink). f Triplex Td viewed from inside of the capsid (left), counterclockwise rotation of Tri2A by 120 degrees about a local threefold axis results in a superposition of clamp and trunk domains from Tri2A to those from Tri2B, suggesting a high level of similarity (right). g Pipe-and-plank representations of Tri2 dimer in side (left panel) and top (right panel) views showing the helix bundle formed from Tri2A and Tri2B’s embracing arm domains. h Two orthogonal views of superposition of Tri2A and Tri2B showing nearly identical clamp and trunk domains, but different embracing arms. See also Supplementary Movie 6.