TABLE 1.
General characteristics of control and HFD rats.
| Control (n = 16) | HFD (n = 17) | Control (n = 16) | HFD (n = 17) | ||
| Body weight (g) | 415 ± 10 | 454 ± 17∗ | Plasma glucose (mmol/L) | 4.7 ± 0.6 | 5.5 ± 0.9 |
| Retroperitoneal fat pad (g) | 4.3 ± 0.5 | 8.7 ± 1.2∗ | Plasma insulin (mU/L) | 14.3+2.7 | 78.0 ± 15.6∗ |
| Epididymal fat pad (g) | 4.3 ± 0.2 | 9.0 ± 1.2∗ | Insulin sensitivity index | 0.54 ± 0.06 | 0.38 ± 0.04∗ |
| Brown adipose tissue (g) | 0.28 ± 0.03 | 0.61 ± 0.08∗ | Plasma leptin (ng/ml) | 358 ± 37 | 2577 ± 356∗ |
| Plasma triglyceride (mmol/L) | 1.1 ± 0.3 | 5.3 ± 1.3∗ | Plasma angiotensin II (pg/ml) | 92.5 ± 34.1 | 298.5 ± 31.4∗ |
| Basal MAP (mmHg) | 93 ± 4 | 103 ± 5 | Basal heart rate (beat/min) | 347 ± 26 | 366 ± 19 |
| Basal Int. RSNA (μv.s) | 2.2 ± 0.3 | 4.2 ± 0.4∗ | 24 h urinary NE (μg) | 2.0 ± 0.3 | 6.2 ± 0.8∗ |
Values are mean ± SE. ∗P < 0.05 vs. control group. MAP, mean arterial pressure; Int RSNA, integrated renal sympathetic nerve activity; NE, norepinephrine.