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. 2019 Nov 19;9:1241. doi: 10.3389/fonc.2019.01241

Table 1.

Comparison of morphological features of lung metastasis (PM) and non- metastasis (NM) in the training and validation datasets.

Training dataset Validation dataset
Characteristics NM PM p NM PM p
Age 59.82 ± 10.530 58.17 ± 11.360 0.382 58.54 ± 12.188 56.06 ± 9.055 0.372
Gender 0.676 0.316
1 42 (57.5%) 34 (54.0%) 13 (46.4%) 19 (59.4%)
2 31 (42.5%) 29 (46.0%) 15 (53.6%) 13 (40.6%)
Lobe location 0.025* 0.507
1 12 (16.4%) 19 (30.2%) 7 (25.0%) 6 (18.8%)
2 12 (16.4%) 10 (15.9%) 4 (14.3%) 10 (31.3%)
3 23 (31.5%) 9 (14.3%) 8 (28.6%) 5 (15.6%)
4 12 (16.4%) 5 (7.9%) 1 (3.6%) 1 (3.1%)
5 14 (19.2%) 20 (31.7%) 8 (28.6%) 10 (31.3%)
Size category <0.001* 0.00% 0.00% 0.095
1 56 (76.7%) 22 (34.9%) 20 (71.4%) 14 (43.8%)
2 10 (13.7%) 24 (38.1%) 4 (14.3%) 10 (31.3%)
3 7 (9.6%) 17 (27.0%) 4 (14.3%) 8 (25.0%)
Long-axis diameter 8.988 ± 3.493 12.662 ± 4.200 <0.001* 9.221 ± 4.422 11.819 ± 4.180 0.023*
Short-axis diameter 5.825 ± 2.144 9.611 ± 9.253 0.001* 5.682 ± 2.031 8.184 ± 3.071 <0.001*
Density <0.001* 0.002*
1 12 (16.4%) 0 (0.0%) 6 (21.4%) 0 (0.0%)
2 15 (20.5%) 2 (3.2%) 6 (21.4%) 2 (6.3%)
3 46 (63.0%) 61 (96.8%) 16 (57.1%) 30 (93.8%)
Contour 0043* 0.011*
1 2 (2.7%) 10 (15.9%) 1 (3.6%) 1 (3.1%)
2 21 (28.8%) 20 (31.7%) 2 (7.1%) 8 (25.0%)
3 29 (39.7%) 19 (30.2%) 11 (39.3%) 19 (59.4%)
4 21 (28.8%) 14 (22.2%) 14 (50.0%) 4 (12.5%)
Border <0.001* <0.001*
1 28 (38.4%) 2 (3.2%) 13 (46.4%) 1 (3.1%)
2 24 (32.9%) 43 (68.3%) 10 (35.7%) 20 (62.5%)
3 21 (28.8%) 18 (28.6%) 5 (17.9%) 11 (34.4%)
Air bronchogram 0.032* 0.178
0 72 (98.6%) 57 (90.5%) 28 (100.0%) 30 (93.8%)
1 1 (1.4%) 6 (9.5%) 0 (0.0%) 2 (6.3%)
Lymphadenopathy 0.032* 0.369
0 72 (98.6%) 57 (90.5%) 27 (96.4%) 29 (90.6%)
1 1 (1.4%) 6 (9.5%) 1 (3.6%) 3 (9.4%)

Chi-square tests were used to compare the differences in categorical variables while a two-sample t-test was used to compare the differences in continuous variables.

NM, non-metastasis group; PM, lung metastasis group.

*

p < 0.05.