Table 2.
Visual acuity before and after transplantation of limbal stem cells
Variable | Autologous cultured LSC transplantation (autoLSC group) | Allogeneic cultured LSC transplantation (alloLSC group) | Autologous limbal tissue transplantation (autoLT group) | Allogeneic limbal tissue transplantation (alloLT group) | p value |
---|---|---|---|---|---|
n | 7 | 7 | 8 | 8 | |
Follow‐up time (months) | 61, 48 [41–80] | 83, 78 [66–101] | 134, 149 [50–218] | 131, 138 [62–200] | .38 |
LogMAR baseline visual acuity | 2.1 (20/2,301), 2.3 (20/4,000) [1.7–2.4] | 2.3 (20/4,263), 2.3 (20/4,000) [1.9–2.8] | 1.6 (20/752), 1.7 (20/894) [1.2–2.0] | 2.2 (20/3,000), 2.3 (20/4,000) [1.9–2.5] | .01 |
LogMAR visual acuity at last exam | 1.1 (20/278), 0.9 (20/143) [0.4–1.9] | 2.4 (20/5,063), 2.3 (20/4,000) [1.8–3.0] | 1.2 (20/348), 0.6 (20/71) [0.2–1.2] | 2.4 (20/4,612), 2.3 (20/4,000) [2.0–2.7] | .02 |
Change in visual acuity from baseline to last exam, lines | +9.2, +11.5 [+2.5 to +15.9] | −0.7, 0.0 [−6.6 to +5.1] | +3.3, +5.5 [−4.5 to +11.2] | −1.9, 0.0 [−7.8 to +4.1] | .08 |
Mean, median, and [95% confidence interval] are shown.
Abbreviations: LogMAR, logarithm of the minimum angle of resolution; LSC, limbal stem cell.