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. 2019 Nov 11;2019:1571392. doi: 10.1155/2019/1571392

Figure 4.

Figure 4

MFX-M alleviates the NLPR3 inflammasome activation in the hippocampus of LPS-stimulated mice. Representative blots and statistical graphs of relative protein expression of NLRP3 (a), ASC (b), cl-caspase-1, pro-caspase-1 (c), IL-1β (d), and TXNIP (e). (f) Frozen sections of brain tissue were subjected to immunofluorescence staining. The hippocampus sections were incubated with anti-GFAP antibody (green), anti-IL-1β (red), and DAPI (blue) and were observed by a laser scanning confocal microscope. Scale bar = 40 μm. Data were the mean ± S.E.M. (n = 3 experimental replicates/group). ∗p < 0.05 and ∗∗p < 0.01 compared to the control group. #p < 0.05 and ##p < 0.01 compared to the LPS group.