Table 2.
Lipid peroxidation inhibitory activity of caffeic acid amides and related compounds.
| Entry | Compound | Structure | IC50 (µM)a | Reference |
|---|---|---|---|---|
| 1 | N-(2-Hydroxyphenyl) caffeamide |
|
0.29 | [44] |
| 2 | N-Phenyl caffeamide |
|
0.38 | [44] |
| 3 | N-(3,4-Dihydroxyphenethyl) caffeamide |
|
0.59 | [44] |
| 4 | N-Isopentyl caffeamide |
|
1.4 | [44] |
| 5 | Trolox |
|
2.8 | [44] |
| 6 | Caffeic acid |
|
3.3 | [44] |
| 7 | Quercetin |
|
0.95 | [44] |
aThe antioxidant activity of each compound was expressed as IC50 value, i.e., the concentration in µM necessary to inhibit TBARS formation by 50%, and was calculated from the corresponding log-dose inhibition curve.