Table 1; online:
Atorvastatin KD subjects (N=9) |
KD controls† (N=18) |
P value | |
---|---|---|---|
Statin concentration 0.125 mg/kg, N | 1 | NA | NA |
0.25 mg/kg, N | 1 | NA | NA |
0.75 mg/kg, N | 7 | NA | NA |
Age, y* | 2.9 (2.8-5.1) | 3.5 (2.5-5.4) | 0.8 |
Males, N (%) | 8 (89) | 13 (72) | 0.6 |
Days of illness at sample collection* | |||
Pre-IVIG | 5 (4-6) | 5 (4-6) | 0.7 |
2 weeks | 20 (20-22) | 20 (17-23) | 0.6 |
White blood cell count, ×109/L* | 11.7 (10.7-13.2) | 10.4 (7.8-14.5) | 0.4 |
CRP, mg/dL* | 8.1 (6.0-10.1) | 5.5 (4.1-17.7) | 1.0 |
ESR, mm/hr* | 60 (33-80) | 42 (27-60) | 0.6 |
ALT, IU/L* | 63 (35-107) | 87 (46-108) | 0.4 |
Zmax* | 3.2 (2.8-3.7) | 2.0 (1.3-2.8) | 0.1 |
Median (IQR)
Controls are KD subjects treated only with IVIG and infliximab
WBC: white blood cell count, ESR: erythrocyte sedimentation rate, CRP: C-reactive protein, ALT: alanine aminotransferase, NA: Not applicable