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. Author manuscript; available in PMC: 2020 Oct 15.
Published in final edited form as: Neuroscience. 2019 Sep 3;418:122–132. doi: 10.1016/j.neuroscience.2019.08.048

Figure 3. Phase plot analysis of the action potential reveals changes in the depolarizing slope following paraquat treatment.

Figure 3.

A. Schematic representation of the phase plot analysis. Top: sample action potential showing the voltage at: rest (Vrest), threshold (Vthresh), peak (Vmax), and repolarization (Vrepol), and the slope for the measurement of depolarizing and repolarizing phases. Bottom: sample phase plot calculated from the above action potential, with the corresponding aforementioned parameters.

B. Representative phase plots from control (black), 10P (blue), and P+L (red).

C. Whisker box plot showing that the slope of repolarization is reduced significantly after paraquat treatment.

Black bar: CTL; blue bar: 10P; red bar: P+L; N=6 cells for all; N=5 animals in control, and N=6 animals in 10P and P+L. *p < 0.05 vs 10P and P+L.