Table I –
Baseline Characteristics of study participants by albuminuria status
| No albuminuria (n=7183) |
Albuminuria (n=1730) |
P-value | |
|---|---|---|---|
| Age (years) | 67.4 (9.2) | 70.3 (10.1) | <0.001 |
| Female (n,%) | 2568 (35.8) | 579 (33.5) | 0.07 |
| Race/ethnic group (n,%) | |||
| Non-Hispanic white | 4121 (57.4) | 995 (57.5) | 0.04 |
| Non-Hispanic black | 2138 (29.8) | 552 (31.9) | |
| Hispanic | 789 (11.0) | 154 (8.9) | |
| Other | 135 (1.9) | 29 (1.7) | |
| Baseline blood pressure (mmHg) | |||
| Systolic | 139±15 | 144±17 | <0.001 |
| Diastolic | 78±12 | 78±13 | 0.16 |
| Antihypertensive agents (n) | 2 (1-2) | 2 (1-3) | <0.001 |
| Cardiovascular disease (n,%) | 1381 (19.2) | 423 (24.5) | <0.001 |
| Body mass index (kg/m2) | 29.9±5.7 | 29.7±6.1 | 0.27 |
| Fasting plasma glucose (mg/dL) | 99±13 | 99±15 | 0.25 |
| Fasting total cholesterol (mg/dL) | 191±41 | 185±42 | <0.001 |
| Fasting high-density lipoprotein cholesterol (mg/dL) | 53±14 | 52±16 | 0.23 |
| Fasting total triglycerides (mg/dL) | 106 (77-149) | 109 (78-157) | 0.02 |
| Statin use (n,%) | 3056 (42.8) | 837 (48.7) | <0.001 |
| Aspirin use (n,%) | 3632 (50.7) | 908 (52.5) | 0.17 |
| Current smoker (n,%) | 3011 (41.9) | 786 (45.4) | 0.01 |
| Estimated glomerular filtration rate (mL/min/1.73m2) | 74±19 | 63±24 | <0.001 |
| Chronic kidney disease (n,%) | 1736 (24.2) | 818 (47.3) | <0.001 |
| Urinary albumin-to-creatinine ratio (mg/g) | 7.7 (5.1-12.6) | 69.7 (42.1-162.1) | <0.001 |