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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Stroke. 2019 Oct 25;50(12):3569–3577. doi: 10.1161/STROKEAHA.119.025898

Table 2.

Performance of different CST injury methods for distinguishing proportional from limited recoverers. Values are presented as mean ± se. Abbreviations for different CST injury methods: Max Area = maximum cross-sectional area, RLL = raw lesion load, WLL = weighted lesion load, 16/5% = 16 divisions, 5% injury threshold

CST Template Injury Method CST Injury Value p
(KS test)+
p
(adjusted)
Proportional
(n=31)*
Limited
(n=17)*
UCI, M1 Max Area 0.47 ± 0.061 0.75 ± 0.060 0.0080 0.017
UCI, M1 RLL (cc) 0.86 ± 0.14 2.0 ± 0.35 0.0034 0.0042
UCI, M1 WLL (cc) 1.42 ± 0.22 3.26 ± 0.56 0.0037 0.0058
UCI, M1 16/5% 0.44 ± 0.063 0.75 ± 0.050 0.0067 0.013
JHU, M1 Max Area 0.36 ± 0.044 0.64 ± 0.061 <0.001 0.0022
JHU, M1 RLL (cc) 0.26 ± 0.04 0.68 ± 0.12 <0.001 0.0037
JHU, M1 WLL (cc) 0.50 ± 0.08 1.23 ± 0.21 0.0011 0.0037
JHU, M1 16/5% 0.21 ± 0.038 0.47 ± 0.080 0.0047 0.0056
PMd Max Area 0.44 ± 0.048 0.66 ± 0.060 0.0070 0.021
PMd RLL (cc) 1.11 ± 0.18 2.52 ± 0.48 0.012 0.0034
PMd WLL (cc) 1.77 ± 0.27 4.02 ± 0.69 0.0022 0.0020
PMd 16/5% 0.39 ± 0.057 0.65 ± 0.084 0.015 0.022
PMv Max Area 0.42 ± 0.060 0.68 ± 0.079 0.012 0.026
PMv RLL (cc) 0.64 ± 0.13 1.51 ± 0.36 0.017 0.0088
PMv WLL (cc) 1.18 ± 0.23 2.90 ± 0.64 0.0053 0.0031
PMv 16/5% 0.37 ± 0.060 0.63 ± 0.085 0.025 0.026
Lesion Volume (cc) 35.0 ± 10.3 53. 6 ± 16.2 0.14 -
*

Note that UCI template calculations could not be performed on 5/48 (3 proportional and 2 limited recoverers) because these participants had injury that extended below the level of the mid-pons. JHU template calculations were performed on all 48 participants.

+

KS test = Kolmogorov-Smirnov test.

logistic regression adjusted for lesion volume.