Table 2.
Performance of different CST injury methods for distinguishing proportional from limited recoverers. Values are presented as mean ± se. Abbreviations for different CST injury methods: Max Area = maximum cross-sectional area, RLL = raw lesion load, WLL = weighted lesion load, 16/5% = 16 divisions, 5% injury threshold
CST Template | Injury Method | CST Injury Value | p (KS test)+ |
p (adjusted) ‡ |
|
---|---|---|---|---|---|
Proportional (n=31)* |
Limited (n=17)* |
||||
UCI, M1 | Max Area | 0.47 ± 0.061 | 0.75 ± 0.060 | 0.0080 | 0.017 |
UCI, M1 | RLL (cc) | 0.86 ± 0.14 | 2.0 ± 0.35 | 0.0034 | 0.0042 |
UCI, M1 | WLL (cc) | 1.42 ± 0.22 | 3.26 ± 0.56 | 0.0037 | 0.0058 |
UCI, M1 | 16/5% | 0.44 ± 0.063 | 0.75 ± 0.050 | 0.0067 | 0.013 |
JHU, M1 | Max Area | 0.36 ± 0.044 | 0.64 ± 0.061 | <0.001 | 0.0022 |
JHU, M1 | RLL (cc) | 0.26 ± 0.04 | 0.68 ± 0.12 | <0.001 | 0.0037 |
JHU, M1 | WLL (cc) | 0.50 ± 0.08 | 1.23 ± 0.21 | 0.0011 | 0.0037 |
JHU, M1 | 16/5% | 0.21 ± 0.038 | 0.47 ± 0.080 | 0.0047 | 0.0056 |
PMd | Max Area | 0.44 ± 0.048 | 0.66 ± 0.060 | 0.0070 | 0.021 |
PMd | RLL (cc) | 1.11 ± 0.18 | 2.52 ± 0.48 | 0.012 | 0.0034 |
PMd | WLL (cc) | 1.77 ± 0.27 | 4.02 ± 0.69 | 0.0022 | 0.0020 |
PMd | 16/5% | 0.39 ± 0.057 | 0.65 ± 0.084 | 0.015 | 0.022 |
PMv | Max Area | 0.42 ± 0.060 | 0.68 ± 0.079 | 0.012 | 0.026 |
PMv | RLL (cc) | 0.64 ± 0.13 | 1.51 ± 0.36 | 0.017 | 0.0088 |
PMv | WLL (cc) | 1.18 ± 0.23 | 2.90 ± 0.64 | 0.0053 | 0.0031 |
PMv | 16/5% | 0.37 ± 0.060 | 0.63 ± 0.085 | 0.025 | 0.026 |
Lesion Volume (cc) | 35.0 ± 10.3 | 53. 6 ± 16.2 | 0.14 | - |
Note that UCI template calculations could not be performed on 5/48 (3 proportional and 2 limited recoverers) because these participants had injury that extended below the level of the mid-pons. JHU template calculations were performed on all 48 participants.
KS test = Kolmogorov-Smirnov test.
logistic regression adjusted for lesion volume.