Table 2. Comparison of patient populations from respective institutions.
Values presented as median (25–75 interquartile range) and n (percent) as appropriate.
| Denver Health (n=61) | Intermountain (n=34) | p value | |
|---|---|---|---|
| Demographics | |||
| Age (years) | 38.0 (26.0–52.5) | 41.5 (24.8–59.5) | 0.49 |
| Male sex, n (%) | 43 (70%) | 27 (79%) | 0.34 |
| Injury | |||
| Mechanism: MVC, n (%) | 22 (36%) | 11 (32%) | 0.01 |
| Mechanism: MCC, n (%) | 12 (20%) | 2 (6%) | |
| Mechanism: fall, n (%) | 11 (18%) | 11 (32%) | |
| Mechanism: auto-pedestrian, n (%) | 12 (20%) | 2 (6%) | |
| Mechanism: bicycle crash, n (%) | 3 (5%) | 2 (6%) | |
| Mechanism: sports injury, n (%) | 0 (0%) | 5 (15%) | |
| Mechanism: other, n (%) | 1 (1%) | 1 (3%) | |
| Injury Severity Score | 27 (20–34) | 26 (17–38) | 0.93 |
| Glasgow Coma Scale | 7 (6–10) | 14 (10–15) | 0.003 |
| Traumatic brain injury, n (%) | 30 (49%) | 13 (38%) | 0.30 |
| Time of Injury to Arrival (min) | 69 (24–204) | 110 (35–206) | 0.26 |
| Initial Physiologic Measurements | |||
| Systolic blood pressure (mm Hg) | 120 (100–140) | 126 (110–140) | 0.43 |
| Base deficit (meq/L) | 6.0 (4.0–10.0) | 5.6 (2.5–10.0) | 0.28 |
| Lactate (mmol/L) | 3.9 (1.6–5.6) | 3.6 (2.3–5.4) | 0.77 |
| Initial Hematology | |||
| Hemoglobin (g/dL) | 12.1 (10.2–13.6) | 13.1 (8.8–17.7) | 0.15 |
| Platelets (10^9/L) | 212 (155–246) | 196 (157–233) | 0.51 |
| Resuscitation in First 24 Hours | |||
| Crystalloids (mL) | 2300 (1000–3815) | 1962 (1040–3443) | 0.54 |
| RBCs (units) | 0 (0–2) | 0 (0–1) | 0.72 |
| FFP (units) | 0 (0–2) | 0 (0–0) | 0.01 |
| Platelets (units) | 0 (0–0) | 0 (0–0) | 0.58 |
| Cryoprecipitate (units) | 0 (0–0) | 0 (0–0) | 0.09 |
| Outcomes | |||
| VTE chemoprophylaxis, n (%) | 54 (89%) | 21 (62%) | 0.009 |
| Time to VTE chemoprophylaxis (hours) | 40.1 (25.8–70.5) | 46.8 (27.4–61.5) | 0.96 |
| Any clot complication, n (%) | 6 (10%) | 6 (18%) | 0.27 |
| DVT, n (%) | 1 (2%) | 6 (18%) | 0.004 |
| PE, n (%) | 1 (2%) | 1 (3%) | 0.67 |
| CVA, n (%) | 4 (7%) | 1 (3%) | 0.45 |
| ICU LOS (days) | 11 (5–15) | 4 (2–7) | <0.001 |
| Hospital LOS (days) | 19 (14–26) | 10 (5–17) | <0.001 |
| Mortality, n (%) | 2 (3%) | 2 (6%) | 0.54 |
MVC=motor vehicle collision, MCC=motorcycle collision, RBCs=red blood cells, FFP=fresh frozen plasma, VTE= venous thromboembolism, DVT=deep venous thrombosis, PE=pulmonary embolus, CVA=cerebrovascular accident, ICU=intensive care unit, LOS=length of stay