Table 4. Dynamic coagulation profile of patients who developed clot complications compared to those who did not.
Values presented as median (25–75 interquartile range).
| No VTE (n=83) | VTE (n=12) | p value | |
|---|---|---|---|
| Hour 12 | |||
| R (min) | 4.8 (4.0–6.6) | 4.5 (3.0–7.9) | 0.96 |
| Angle (degrees) | 70.6 (65.8–74.9) | 73.0 (64.1–74.1) | 0.73 |
| MA (mm) | 66.5 (62.4–69.4) | 68.1 (62.1–69.5) | 0.95 |
| LY30 (%) | 0.9 (0.4–1.7) | 0.2 (0.0–0.5) | 0.02 |
| Hour 24 | |||
| R (min) | 5.1 (3.8–6.2) | 4.1 (3.0–6.6) | 0.44 |
| Angle (degrees) | 70.4 (67.2–73.2) | 70.8 (63.4–72.7) | 0.81 |
| MA (mm) | 66.5 (63.2–69.0) | 66.2 (61.9–71.2) | 0.88 |
| LY30 (%) | 1.4 (0.5–2.0) | 0.6 (0.1–2.2) | 0.25 |
| Hour 36 | |||
| R (min) | 5.5 (3.9–6.8) | 3.4 (2.8–6.7) | 0.05 |
| Angle (degrees) | 71.1 (68.5–72.9) | 72.8 (69.7–76.2) | 0.21 |
| MA (mm) | 67.5 (64.2–70.5) | 67.8 (66.1–71.1) | 0.64 |
| LY30 (%) | 1.5 (1.1–2.0) | 1.3 (0.4–2.4) | 0.56 |
| Hour 48 | |||
| R (min) | 5.9 (4.3–7.1) | 8.2 (3.9–12.3) | 0.42 |
| Angle (degrees) | 70.3 (66.9–72.6) | 66.2 (52.4–74.1) | 0.44 |
| MA (mm) | 68.5 (64.6–71.5) | 71.9 (69.5–76.0) | 0.04 |
| LY30 (%) | 1.4 (0.9–2.5) | 0.6 (0.2–1.8) | 0.16 |
| Hour 60 | |||
| R (min) | 5.8 (4.3–6.5) | 4.9 (4.0–6.6) | 0.65 |
| Angle (degrees) | 71.3 (68.5–73.4) | 71.1 (68.5–73.4) | 0.96 |
| MA (mm) | 69.5 (63.7–71.5) | 71.0 (68.0–74.5) | 0.48 |
| LY30 (%) | 1.3 (0.3–2.1) | 1.8 (0.4–2.6) | 0.41 |
| Hour 72 | |||
| R (min) | 6.0 (4.4–7.1) | 7.7 (4.4–9.9) | 0.52 |
| Angle (degrees) | 71.1 (68.1–73.2) | 64.6 (60.6–73.8) | 0.30 |
| MA (mm) | 72.5 (69.4–75.8) | 72.6 (70.5–74.7) | 0.95 |
| LY30 (%) | 1.1 (0.7–2.1) | 0.9 (0.5–2.0) | 0.77 |
| Hour 84 | |||
| R (min) | 5.8 (4.7–7.2) | 6.4 (3.9–7.4) | 0.58 |
| Angle (degrees) | 71.4 (68.0–74.1) | 70.2 (65.8–74.4) | 0.86 |
| MA (mm) | 73.1 (69.5–76.0) | 74.0 (70.0–76.8) | 0.89 |
| LY30 (%) | 0.8 (0.4–1.8) | 1.6 (0.7–2.7) | 0.19 |
| Hour 96 | |||
| R (min) | 6.6 (4.8–7.8) | 8.1 (4.6–10.2) | 0.37 |
| Angle (degrees) | 72.2 (68.5–75.0) | 72.4 (64.1–77.7) | 0.70 |
| MA (mm) | 75.0 (72.0–79.0) | 75.4 (73.0–81.0) | 0.52 |
| LY30 (%) | 1.0 (0.5–1.7) | 0.5 (0.1–1.6) | 0.57 |
| Hour 108 | |||
| R (min) | 6.2 (4.9–8.0) | 7.4 (5.6–9.7) | 0.38 |
| Angle (degrees) | 71.7 (67.6–74.2) | 69.3 (64.1–74.0) | 0.61 |
| MA (mm) | 73.9 (71.1–77.1) | 75.0 (73.0–78.1) | 0.59 |
| LY30 (%) | 0.9 (0.2–1.6) | 0.7 (0.0–1.2) | 0.44 |
R=reaction time, MA=maximum amplitude, LY30=lysis 30 minutes after MA