rs6295-dependent differences in rearing in open field are line specific. In open field, line A had no statistically significant difference in (A) rearing, (B) time spent in the center, or (C) percentage distance traveled in the center between genotypes. (D) Likewise, there was no main or interacting effect of genotype on distance traveled over time. (E) In line B, CC animals reared more than GG animals (p = 0.016). There were no differences in other measures of anxiety, specifically (F) time spent in the center or (G) percentage distance traveled in the center between genotypes. (H) There was no main or interacting effect of genotype on distance traveled over time (group sizes and statistics available in Supplementary Table 4). Values represent mean ± SEM.