CCR7 trap efficiently inhibited lymph node metastasis of B16F10 melanoma cells. a) Tumor growth curve with three treatments on day 9, 11, and 13 (**, p < 0.01; n = 6). b) Volume comparison of LNs, B16F10 tumor cell metastasis of LNs, and proportion of metastasis positive mice at the endpoint. c) H&E staining of B16F10 tumor cell metastasis (yellow circle) in sentinel LNs at the endpoint.