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. Author manuscript; available in PMC: 2019 Nov 26.
Published in final edited form as: Cell Rep. 2018 Oct 30;25(5):1225–1240.e6. doi: 10.1016/j.celrep.2018.10.012

Figure 7. DAZL Binds and Regulates a Broad Network of Essential Genes Encoding Interacting Proteins.

Figure 7.

(A) Hierarchical clustering of enriched GO terms and genes associated with the set of 501 genes that are enhanced by DAZL and have DAZL-3′ UTR interactions. Subgroups of overlapping GO categories are indicated at left, while subgroups of genes are indicated with letters at bottom.

(B) List of all of the genes in each letter group indicated at the bottom of (A).

(C) Protein-protein interaction network for genes with DAZL-3′ UTR interactions and reduced RNA levels in Dazl KO cells compared to WT controls.