Table I.
Variables | Primary tumor (N=123) (%) | Deposits of cancer cells (N=25) (%) | Liver metastases (N=15) (%) |
---|---|---|---|
Age (years) | |||
<60 | 29 (23.7) | 6 (24) | 1 (6.6) |
>60 | 94 (76.3) | 19 (76) | 14 (93.4) |
Sex | |||
Female | 48 (39.0) | 10 (40) | 5 (33.3) |
Male | 75 (61.0) | 15 (60) | 10 (66.7) |
Localization | |||
Right-side | 13 (10.5) | 3 (12) | 2 (13.3) |
Transverse | 5 (4.0) | 1 (4) | 1 (6.6) |
Left-side | 4 (3.2) | 1 (4) | 2 (13.3) |
Sigmoid | 21 (17.3) | 5 (20) | 1 (6.6) |
Rectum | 80 (65.0) | 15 (60) | 9 (60.2) |
Tumor growth | |||
Expanding | 103 (83.7) | 20 (80) | 13 (98.7) |
Infiltrate | 20 (16.3) | 5 (20) | 2 (1.3) |
Tumor size | |||
<2.5 cm | 20 (16.3) | 3 (12) | 2 (1.3) |
2.5–5.0 cm | 81 (65.8) | 20 (80) | 13 (98.7) |
>5.0 cm | 22 (17.9) | 2 (8) | 0 (0) |
TNM stage | |||
1 | 17 (13.8) | 0 (0) | 0 (0) |
2 | 43 (34.9) | 0 (0) | 0 (0) |
3 | 58 (47.1) | 21 (84) | 0 (0) |
4 | 2 (4.2) | 4 (16) | 15 (100) |
Lymph node metastasis | |||
Absent | 65 (52.8) | 1 (4) | 6 (39.8) |
Present | 58 (47.2) | 24 (96) | 9 (60.2) |
Distant metastasis | |||
Absent | 123 (100) | 21 (84) | 0 (0) |
Present | 0 (0) | 4 (16) | 15 (100) |
No. of metastases | |||
Single | 0 (0) | 3 (75) | 8 (53.4) |
Multiple | 0 (0) | 1 (25) | 7 (46.6) |
Distant metastasis size (mm) | |||
<5 | 0 (0) | 1 (33.3) | 7 (46.6) |
>5 | 0 (0) | 2 (66.7) | 8 (53.4) |
Tumour deposits | |||
Absent | 123 (100) | 0 (0) | 11 (63.7) |
Present | 0 (0) | 25 (100) | 4 (36.3) |
Preoperative treatment | |||
Yes | 40 (32.6) | 7 (28) | 3 (2) |
No | 83 (67.4) | 18 (72) | 12 (80) |
Type of preoperative treatment | |||
CHT | 5 (14) | 2 (28.5) | 0 (0) |
RHT | 29 (70) | 1 (14.2) | 3 (100) |
RHT+CHT | 6 (16) | 4 (57.3) | 0 (0) |
Preoperative treatment response | |||
SD | 13 (26) | 3 (60) | 2 (66.7) |
PR | 17 (24) | 2 (40) | 1 (33.3) |
Postoperative treatment | |||
Yes | 46 (37.3) | 5 (20) | 8 (53.4) |
No | 77 (62.7) | 20 (80) | 7 (46.6) |
Type of postoperative treatment | |||
CHT | 40 (86.9) | 5 (100) | 6 (75) |
RHT | 2 (4.5) | 0 (0) | 1 (12.5) |
RHT+CHT | 4 (8.6) | 0 (0) | 1 (12.5) |
Disease-free survival | |||
<6 months | 38 (30.8) | 9 (36) | 6 (40) |
6–12 months | 27 (22.9) | 5 (20) | 3 (20) |
>12 months | 57 (46.3) | 11 (44) | 6 (40) |
RHT, radiotherapy; CHT, chemotherapy; SD, stable disease; PR, progression of disease.