Table V.
Effect of polaprezinc on the recovery of the blood hemogram in mice with UC induced by dextran sodium sulfate.
| Group | Total WBC (×109/l) | Neutrophil granulocyte (%) |
|---|---|---|
| Vehicle control | 5.70±0.53 | 23.33±1.94 |
| UC only | 8.32±2.42a | 34.96±9.90a |
| UC + MES | 7.86±1.05 | 31.36±11.08 |
| UC + PZ L | 7.20±1.50 | 27.54±10.86 |
| UC + PZ H | 6.73±1.14 | 19.4±6.50b |
n=8 mice/experimental group.
a
P<0.05 vs. vehicle control
b
P<0.05 vs. UC only. H, high-dose; L, low-dose; MES, mesalamine; PZ, polaprezinc; UC, ulcerative colitis.