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. 2019 Nov 19;10:2655. doi: 10.3389/fimmu.2019.02655

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Copyright © 2019 Vagnerová, Vodička, Hermanová, Ergang, Šrůtková, Klusoňová, Balounová, Hudcovic and Pácha.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of microbiota and acute restraint stress on expression of genes participating in ileal steroidogenesis and its regulation. For further details, see the description of Figure 3. All data are expressed as mean ± SEM. Where an interaction effect was observed, the ampersand sign (^&&&p < 0.001, ^&&p < 0.01, ^&p < 0.05) indicates a significant difference from the stressed GF mice. Where no interaction effect was observed, a main effect of microbiome has been identified by placing a dashed horizontal line with a hash sign (^##p < 0.01) above the bars for the SPF groups. No main effects of stress were found in any of the analyses.