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Increasing the strength of selection during an E&R study enhances the power to identify QTNs. (A) Approach for identifying the best increasing regime. We evaluated the performance of all possible increasing regimes using steps of 10% (left panel). The best selection regime (bold) has the largest AUC (right panel). (B) The best increasing regime outperforms the evaluated constant regimes (steps of 10%). (C) Performance of each evaluated increasing regime (pAUC).
