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Knockdown of TIGAR modifies cell cycle progression. (A,B) Flow cytometry to analyze the alterations of cell cycle distribution by TIGAR knockdown. Cell cycle progression was modified after shRNA-mediated TIGAR knockdown (C,D) Quantification data of cells distributed at each stage of cell cycle. There is an increase in G2/M fractions. *p < 0.05, **p < 0.01.
