Table 1.
Clinical Characteristics Of Patients With Clinically Stable Bronchiectasis And Healthy Subjects
| Parameter | Bronchiectasis Patients | Healthy Subjects | P value |
|---|---|---|---|
| No. of subjects | 82 | 9 | – |
| PA colonization (No., %) | 34 (41.5%) | NA | NA |
| Anthropometry | |||
| Age (years) | 45.4±14.0 | 45.8±16.5 | 0.352 |
| Females (No., %) | 49 (59.8%) | 4 (44.4%) | 0.483 |
| Body-mass index (kg/m2) | 20.2±2.8 | 22.6±2.0 | 0.432 |
| Never-smokers (No., %) | 6 (7.3%) | 1 (11.1%) | 0.530 |
| FEV1 predicted% | 57.7±22.3 | 95.4±8.8 | <0.001 |
| Exacerbation history | |||
| No. of exacerbations within 1 yr | 1.4±1.1 | NA | NA |
| Severity | |||
| Bronchiectasis Severity Index | 6.6±4.0 | NA | NA |
| E-FACED score | 3.7±1.9 | NA | NA |
| Modified Reiff score | 9.8±4.1 | NA | NA |
| Aetiology | |||
| Idiopathic (No., %) | 25 (30.5%) | NA | NA |
| Post-infectious (No., %) | 33 (40.2%) | NA | NA |
| Kartagener syndrome (No., %) | 8 (9.8%) | NA | NA |
| Asthma (No., %) | 2 (2.4%) | NA | NA |
| Immunodeficiency (No., %) | 5 (6.1%) | NA | NA |
| GORD-aspiration (No., %) | 4 (4.8%) | NA | NA |
| Others (No., %)a | 7 (8.5%) | NA | NA |
| Bacteria isolated during the initial visit | |||
| Pseudomonas aeruginosa | 36 (43.9%) | NA | NA |
| Haemophilus influenzae | 9 (11.0%) | NA | NA |
| Escherichia coli | 4 (4.9%) | NA | NA |
| Other pathogensb | 7 (8.5%) | NA | NA |
| Commensal | 26 (31.7%) | NA | NA |
| Sputum physical characteristic | |||
| Viscosity score | 2.5±0.7 | 2.3±0.9 | 0.747 |
| Purulence score | 6.2±0.9 | 4.0±0.5 | <0.001 |
Notes: P-value for comparisons between patients with clinically stable bronchiectasis and healthy subjects. Othersa included congenital airway defects, diffuse panbronchiolitis and connective tissue disease. bOther pathogens included Klebsiella pneumiae, Proteus mirabilis, Streptococcus pneumoniae, Haemophilus parainfluenzae, Haemophilus parahaemolyticus, Sphingomonas sphingomonas, Enterobacter aerogenes.
Abbreviations: E-FACED, exacerbation-FACED; GORD, gastroesophageal reflux disease-aspiration.