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. 2019 Nov 22;14:2563–2573. doi: 10.2147/COPD.S219821

Table 2.

Multiple Linear Regression Between The DEMs Associated With PA Colonization And Other Clinical Parameters

miRNA ID Adjusted R2 P-value Of The Model Predictor Variables Β P value Of β
miR-23a-3p 0.170 0.005 Age 21.46 0.099
Sex 220.09 0.550
BMI −95.53 0.150
FEV1 pred% −17.69 0.107
No. of lobes affected 32.10 0.877
HRCT Reiff scores −15.19 0.849
PA colonization 982.60 0.012
Other bacterial colonization −11.50 0.983
miR-92b-5p 0.127 0.020 Age 4.88 0.490
Sex 57.74 0.775
BMI 69.43 0.058
FEV1 pred% −5.19 0.386
No. of lobes affected 119.62 0.296
HRCT Reiff scores −76.27 0.086
PA colonization −541.08 0.011
Other bacterial colonization −491.09 0.102
miR-548f-3p 0.116 0.028 Age 0.68 0.135
Sex −0.30 0.981
BMI −0.76 0.745
FEV1 pred% −0.394 0.306
No. of lobes affected −3.83 0.601
HRCT Reiff scores 3.11 0.272
PA colonization 31.03 0.023
Other bacterial colonization 26.80 0.163
miR-223-3p 0.197 0.002 Age 30.51 0.106
Sex −336.37 0.529
BMI −102.57 0.286
FEV1 pred% −23.80 0.135
No. of lobes affected 49.27 0.870
HRCT Reiff scores 26.99 0.816
PA colonization 1748.27 0.002
Other bacterial colonization 930.22 0.239
miR-628-5p 0.164 0.006 Age 0.22 0.478
Sex 5.12 0.555
BMI 0.52 0.740
FEV1 pred% −0.27 0.286
No. of lobes affected 0.726 0.882
HRCT Reiff scores 0.72 0.704
PA colonization 27.37 0.003
Other bacterial colonization −2.93 0.818

Note: P-value that corresponded to the β value of less than 0.05 is presented in bold.

Abbreviations: BMI, body mass index; FEV1, forced expiratory volume in 1 s; PA, P. aeruginosa.