Effects of acute C1 esterase inhibitor (C1-INH) treatment after status epilepticus (SE) on open field (OF) outcomes. The OF test was performed at 3 (A-D) and 14 days (E-H) after SE in control, SE, and SE+C1-INH rats. Distance traveled (A, E) and average speed (B, F) measured locomotion. Time freezing (C and G) and time spent in outer portion of the OF chamber (outer duration) (D, H) measured anxiety-like behaviors. Data are shown as mean +/− standard error of the mean. *, p < 0.05 by one-way ANOVA with Tukey’s post hoc test. Controls, N=14; SE, N=16; SE+C1-INH, N=14.